中文Ọhụrụ Coronavirus Variant Strain 501Y-V2 nke South Africa
Na Disemba 18, 2020, South Africa achọpụtala mutant 501Y-V2 nke coronavirus ọhụrụ.Ugbu a mutant South Africa agbasawo ihe karịrị mba 20.Nnwale egosila na n'elu New Corona-virus Mutants nwere ike iburu ụdị Coronavirus ọhụrụ ndị ọzọ nke K417N/T, E484K na N501Y mutations nke nwere ike ibelata ikike nkwụsị nke ọgwụ mgbochi na-ebute plasma na-egbochi mgbochi.Otú ọ dị, e jiri ya tụnyere genome Wuh01 (ọnụọgụ usoro MN908947), 501Y.V2 nke South Africa mutant genome usoro nwere 23 nucleotide variants.Ọ nwere otu N501Y mutation dị ka Britain mutant B.1.1.7 sub-ụdị, ma ka nwere mutations na abụọ isi saịtị E484K na K417N nke S protein nwere ike dị mkpa mmetụta na ike nke nje ibunye.
Coronavirus ọhụrụ ahụ bụ Nje Virus RNA nwere otu eriri, nke mmụgharị genome na-adịkarị.Nchọpụta otu ebumnuche nwere ike iduga n'ụzọ dị mfe n'ịchọta ihe nlele nke nwere obere nje virus na ụdị nje mutated.Ọnụ ọgụgụ nke nyochaghachi na otu ihe dị mma na nchọpụta ebumnuche, nwere ike iru karịa 10%, nke nwere ike ime ka ọrụ dịkwuo elu ma mee ka oge nyocha ahụ dịkwuo ogologo.Nchọpụta ọtụtụ ebumnuche na nkwenye n'otu n'otu nke nsonaazụ nke ebumnuche ọ bụla nwere ike ime ka ọnụọgụ nchọpụta dị elu ma mee ka nchọpụta mmalite dị mfe.
Onyonyo 1. Eserese eserese nke usoro ọrịa Coronavirus ọhụrụ
Mutant Coronavirus ọhụrụ B.1.1.7 nke Britain
Na Disemba 26, 2020, akwụkwọ sayensị izizi nke B.1.1.7 Strain ka ebipụtara n'ịntanetị.The Institute of Hygiene University of London UK na Tropical Diseases, kwadoro na B.1.1.7 Strain nwere ike gbasaa karịa ụdị ndị ọzọ, nke karịrị 56% (95% CI 50-74%).N'ihi na ụdị mutant ọhụrụ a nwere ike nnyefe doro anya karị, ọ na-esiwanye ike ịchịkwa COVID-19.N'echi ya, Mahadum Birmingham dị na United Kingdom bulitere akụkọ na MedRxiv.Nnyocha ahụ chọpụtara na ọnụ ọgụgụ nke mkpụrụ ndụ nje virus ORF1ab na N na ndị ọrịa butere B.1.1.7 mutant strain (S-gene dropout) mụbara nke ukwuu;A na-enyocha ihe omume a na ndị mmadụ.Edemede a na-akọwa na ndị ọrịa butere mutant B.1.1.7 nke Britain nwere ibu nje dị elu nke ukwuu, yabụ mutant a nwekwara ike bụrụ nke nje.
Ọgụgụ 2. Usoro mmụgharị genome dị na coronavirus mutant strain B.1.1.7 nke Britain
Ọnụọgụ 3. N501Y mmụkọ mere na Britain na South AfricaỤdị dị iche iche
Ngwa nchọpụta nke Coronavirus ọhụrụ dị iche iche
Chuangkun Biotech Inc. emeputala ngwa nchọpụta nke ọma maka ụdị coronavirus ọhụrụ B.1.1.7 na 501Y-V2.
Uru nke ngwaahịa a: elu uche, n'otu oge nchọpụta nke 4 lekwasịrị anya, na-ekpuchi isi mutation saịtị nke B.1.1.7 mutant strain na 501Y.V2 South African mutant strain.Ngwa a nwere ike n'otu oge chọpụta N501Y, HV69-70del, E484K mutation saịtị na ọhụrụ coronavirus S gene;Nnwale ngwa ngwa: ọ na-ewe naanị 1 hour 30 nkeji site na nchịkọta sample iji rụpụta ya.
Ọgụgụ 4. Nchọpụta COVID-19 Britain Variant Amplification Curve
Ọgụgụ 5. Nchọpụta COVID-19 South Africa Variant Amplification Curve
Ọgụgụ 6. Ụdị anụ ọhịa nke New coronavirus amplification curve
O doghị anya ka mmụgharị ndị a si achịkọta mmetụta ogologo oge ọhụụ nke oria ojoo COVID-19 ziri ezi.Mana nke a na-echetara anyị na mmụgharị ndị a nwere ike imetụta ịdị irè nke mgbochi ebumpụta ụwa na mgbochi nke ọgwụ mgbochi na-ebute.Ọ na-echetakwara anyị na anyị kwesịrị ịnọgide na-enyocha coronavirus ọhụrụ ruo ogologo oge ma melite ọgwụ COVID-19 iji merie mgbanwe nke coronavirus ọhụrụ.
Oge nzipu: Mar-12-2021